Harold Ramis Dies At 69: Bill Murray, Dan Akyord, Andie MacDowell And More React To The 'Ghostbusters' Actor's Death On Twitter

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Harold Ramis, best known for his work in "Ghostbusters", "Groundhog Day", "National Lampoon's Vacation", and "Caddyshack", dies at the age of 69. Harold Ramis' cause of death according to his wife, Erica Mann, was due to complications of his "autoimmune inflammatory vasculitis", a rare disease that involves the swelling of blood vessels.

Various celebrities and friends reacted to Harold Ramis death which includes Bill Murray, Dan Akyord, Andie MacDowell, and more just to name a few.

A true comedy Renaissance man, Harold Ramis was a towering influence in Hollywood with a streaks of hits that stretched from the 1978 classic "Animal House," which he wrote, to 1984's blockbuster "Ghostbusters," which he wrote and starred, up to the 1999 hit "Analyze This," and its sequel "Analyze That," to whic he wrote and directed.

In a statement made by his Ghostbusters co-star and close friend, Bill Murray.

"Harold Ramis and I together did the National Lampoon Show off Broadway, Meatballs, Stripes, Caddyshack, Ghostbusters and Groundhog Day. He earned his keep on this planet. God bless him."

Ramis's other Ghostbuster co-star Dan Akyord also said that,

"Deeply saddened to hear of the passing of my brilliant, gifted, funny friend, co-writer/performer and teacher Harold Ramis."

Groundhog Day and Multiplicity star Andie MacDowell also shared his thoughts on Ramis.

"I was fortunate to be able to do two movies with Harold Ramis. He was the kindest of any director with whom I worked. Harold was a genius. On top of his talent, he could do the New York Times crossword puzzle faster than anyone!! I am lucky to have known him as well as I did. I will miss him."

A Chicago native, Ramis moved back to his hometown with his family in 1996. "I feel like I represent the city in a certain way," he said a few years later.

In 2010 Ramis began having health problems following an infection that ultimately caused his rare condition.

Many well known stars and personalities have taken to Twitter and expressed their feelings on Ramis's death. Here are the tweets below.

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