Looks like the Amazing Spider-Man spin-off titles are adding a new player in the mix in the form of the psychotic alien super villain Carnage and is there a possibility that Gwen Stacy would be the Carnage in the spin-off.
With Venom and Sinister Six spin-offs scheduled to be shown before The Amazing Spider-Man 4, it looks like Sony will raise the bar of adding Carnage in the Venom spin-Off. Although no official statement on how Sony will approach the Venom spin-off, It's most likely that it would be based on the Ultimate Marvel Comics were in it was artificially made as seen in the Amazing Spider-Man 2 Trailer were Screenrant uploaded a photo of the scene.
As we all know from the comics that Carnage is the son of Venom, the arch nemesis of Spider-Man and his human host is Cletus Cassidy, a mass murderer. He was considered to be more dangerous than his father and a formidable foe for Spider-Man, that it took both of them to fight and take down Carnage.
But Cletus Cassidy isn't the only Carnage in the Marvel universe. In the Ultimate Marvel Universe, Gwen Stacy became Carnage after the latter was killed by the symbiote and upon her return from the dead became Carnage herself.
Is this a sign of things to come as there could be a possibility that Emma Stone's character will become the alien symbiote villain? Well Marvel fans you'd be the judge.