Chicago White Sox vs. Colorado Rockies WATCH FREE Major League Baseball Live Streaming Online from Coors Field in Denver at 8:40 PM ET

Colorado (3-4) certainly has endured its share of struggles against AL opponents in recent seasons, dropping 28 of 35 meetings -- including 16 of 19 at home -- the past two seasons.

The Rockies went 5-15 overall in those matchups in 2013 on the way to their second straight last-place finish in the NL West. They went 42-29 with a 4.35 ERA at home against NL foes, but finished 3-7 with a 5.04 mark there when facing the AL.

Jordan Lyles will try to get the Rockies off to a good start in interleague play as he takes the mound for the second time since coming over in the December trade that sent Dexter Fowler to Houston.

Lyles, however, has gone just 6-12 with a 5.63 ERA in 26 career starts against AL opponents. In his only start against the White Sox (3-3), he coughed up five runs over 4 1/3 innings in a 10-1 road loss June 9, 2012, while with the Astros.

The right-hander managed to get a win in his Colorado debut despite allowing four runs in five innings of a 6-5 victory in Miami on Wednesday. Now he'll have to deal with a Chicago lineup that has hit .278 while averaging 5.7 runs.

Felipe Paulino hopes to give Chicago its second straight outstanding performance after Chris Sale gave up four singles in eight scoreless innings in a 5-1 win at Kansas City on Sunday.

Paulino, who spent the 2010 season with Colorado, has surrendered 16 runs and 26 hits over 18 1/3 innings in nine career games -- two starts -- at Coors Field.

Chicago has won five of six meetings in Colorado, last taking two of three in June 2011.

The game will be live streaming online atwww.stream2watch.me › baseball‎